Rheumatoid Arthritis: Are Current Research-based Guidelines Clinically Relevant?

Rheumatoid arthritis: are current research-based guidelines clinically relevant?

Clinically relevant advances in rheumatoid arthritis therapy

Owing to the success of biologics in the treatment of rheumatoid arthritis (RA), several novel drugs have been introduced in the therapeutic armamentarium, although not all of them have been approved in all countries worldwide. Among the drugs are tumour necrosis factor (TNF) inhibitors such as certolizumab pegol and golimumab (the latter of which was the first TNF blocker shown to be effective...

Prognostic Factors Toward Clinically Relevant Radiographic Progression in Patients With Rheumatoid Arthritis in Clinical Practice

To determine prognostic factors of clinically relevant radiographic progression (CRRP) in patients with rheumatoid arthritis (RA) in clinical practice.We performed a multicenter prospective study in Japan of biological disease-modifying antirheumatic drug (bDMARD)-naive RA patients with moderate to high disease activity treated with conventional synthetic DMARDs (csDMARDs) at study entry. We lo...

"Rheumatoid Arthritis": A balanced overview of current research

This is a brief review of the third volume of the series edited by AN Theofilopoulos, “Current Directions in Autoimmunity”. This hard-cover volume comprises 282 pages, 46 figures and 14 tables. The book has a cover price of 196 Swiss Francs, or 255 Deutschmarks, or 170.50 US dollars. Received: 17 April 2001 Accepted: 17 April 2001 Published: 26 April 2001 Arthritis Res 2001, 3:241 © 2001 BioMed...

Toward more clinically relevant assessment research.

The purpose of this article is to encourage the design and conduct of more clinically relevant assessment research. The discussion focuses on the distinction between research design elements that are appropriate to the examination of validity versus utility issues in assessment. This was addressed in 2 ways. The first part of the article summarizes the results of an informal methodological revi...